The best way to reach Infante Sagres Porto Hotel from Lisbon is by Private Transfer.
From Lisbon, you can request pickup at your hotel/accommodation front door, or airport, with your luggage, directly to your destination in Porto, without the hassle of public transportation and crowds.
Any destination place in the Porto/Gaia can be covered.
We cover many hotels, such as: Yeatman, Pestana Palace, Infante Sagres, Intercontinental, Maison Albar Monumental Palace, Sheraton, and much more.
There are three options to consider:
OPTION #1: Direct Transfer (Private), no stops (by LisbonGuide / Concierge Portugal): https://lisbonguide.org/private-transfers-portugal/
OPTION #2: Private Transfer, by Portugal Magik Tours: https://portugal-magik.com/tour/private-driver-transfer-from-lisbon-to-porto/
OPTION #3: Car + Driver at your disposal with Portugal Magik (Ideally for multiple days): https://portugal-magik.com/tour/driver-portugal/
You can also follow here this app, for instant quotation and booking: https://lisbon.ridebitsapp.com/central/new_reservation
Enjoy Lisbon and Porto. Make sure to travel in comfort and safety.