From Lisbon, the best way to reach Six Senses Douro Valley is by Private Transfer.
You can see here below the best options, starting at 550EUR.
The driving time takes approximately 4h, by highway, including pickup at your hotel in Lisbon (or airport, on on request), finishing at your hotel Six Senses.
Private Transfer from Lisbon to Six Senses Douro Valley: Reservation Link
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